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10-year risk estimates for dementia, says study

New Delhi, Sep 04 (ANI): According to a new study, 10-year absolute risk estimates for dementia, which is specific to age and sex. It may help identify high-risk individuals who could potentially benefit from early targeted prevention. Dementia is a major cause of disability, generally found in older people, yet no effective treatment is currently available. Reduction of risk factors for dementia, however, can delay or prevent the development of the disease. The apolipoprotein E (APOE) protein is key for metabolising cholesterol. It also helps to clear ß-amyloid protein from the brain in individuals with Alzheimer’s disease. Researchers found that a combination of age, sex and a common variation in the APOE gene could identify high-risk groups, with a 7 per cent risk for women and 6 per cent risk for men in their 60s; a 16 per cent and 12 per cent risk, respectively, for people in their 70s; and a 24 per cent and 19 per cent risk, respectively, for those aged 80 years and older. The findings appeared in the Journal of the Canadian Medical Association.

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