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Proteins found in animals can help enhance gum healing

Washington, Mon, 05 Mar 2012 ANI

Washington, March 5 (ANI): A novel method using collagen - a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals - can heal receding gums and exposed roots, say researchers.


Receding gums often result in tooth sensitivity and can lead to decay of the root and persistent inflammation of the gum.


Researchers across Germany and Switzerland led by Dr Shahram Ghanaati and the dentist Dr Markus Schlee investigated the possibility of using collagen, extracted from bovine pericardium, to form a support for mending receding gums and exposed roots.


The pericardium is a thin membrane surrounding the hearts of all mammals. The bovine pericardium is principally composed of collagen.


The collagen was extracted by a process involving osmotic, oxidative and alkaline treatment.


This ensured that the cell walls were broken down, proteins and fats dissolved, and that bacteria, viruses and other pathogens were inactivated and removed.


The study followed 14 otherwise healthy patients with over 60 'recessions' between them. Their damaged teeth were cleaned before surgery and the collagen implants held in place with loops of surgical thread around the affected tooth. Two weeks later the sutures were removed. None of the patients needed antibiotics.


The patients were re-examined after six months to see how well they had recovered.


"In all cases the healed-over implant improved the look and severity of the recession, and, in over half of all treatments, resulted in total coverage of the exposed root. We would not have expected any of these patients to get better without surgery," said Dr Schlee.


The collagen seems to be able to act as a scaffold for the body's own cells to repair the damage leading to results on a level comparable to that of connective tissue grafts. Bovine collagen is a possible solution for patients with little available donor tissue or for whom multiple surgeries are not an option.


The results were published in BioMed Central's open access journal Head and Face Medicine. (ANI)


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