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Now science has an answer for your insatiable appetite

New Delhi, Jun 03 (ANI): Many complain or boast about their insatiable appetite, science has found the reason. A USC study shows the brain's plumbing system serves double duty, flushing waste and channeling a hunger molecule that tells you when you should eat. The study shows that the brain regulates some processes by releasing and dispersing molecules, and in this case, a Neuropeptide, through cerebrospinal fluid. Drug developers are interested in creating pharmaceuticals that would target the melanin-concentrating hormone (MCH) system to control appetite, and thereby address obesity and other weight-related health problems. Cerebrospinal fluid has three chief assignments. First, its grueling eternal task is buoyancy, like the Greek Titan Atlas, supporting the brain. Second, it acts as a cushion after a blow to the head. Third, it is the brain's sewer system, clearing away metabolic waste. MCH stimulates appetite. It also can slow energy expenditure. Through a series of experiments with rats, the researchers stimulated release of the hunger peptide and then tracked it in the cerebrospinal fluid. Based on their findings, the researchers determined the peptide's release is likely influenced by circadian clock and a daily mealtime routine. The study has been published in the journal Cell Metabolism.

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