Antibiotic sets up roadblock to kill bacteria
Washington Oct 25 (IANS) Scientists have edged closer to developing more effective drugs by identifying how an antibiotic sets up roadblocks to halt bacterial growth.
Until now, researchers did not know the mechanism behind how the antibiotic actually killed the bacteria.
For example, myxopyronin, an antibiotic, is a natural substance generated by bacteria to fend off other bacteria. It is known to have inherited the actions of an enzyme called RNA polymerase, which activates gene expression and is essential for a cell's life.
Key to investigating this mechanism is the use of the powerful imaging technique X-ray crystallography, which allows researchers to see the fine details of the linkage between the antibiotic and its target, according to an Ohio State release. The study was published online in Nature.
'This is the first antibiotic that we know that inhibits polymerase before it even starts RNA synthesis,' said Irina Artsimovitch, a co-author of the study and an associate professor of microbiology at Ohio State University.
Read More: University Grants Commission (UGC) | Guru Nanak Dev University | Charkhari State | Sarila State | University Po | Kumaon University Nainital | Mahdaiya State | Gorakhpur University | Agra University | Ayurvedic University | Bundelkhand University So | Mds University Ajmer Dtso | State Bank Of Hyderabad | State Bank Of India | State Bank Of Mysore Colony | State Bank Colony | State Farm Colony | North Bengal University So | Kalyani University | Guwahati University Ho
Celebrity News - 9/7/2014
July 10, 2014 at 11:15 AM
10 July 2014 - View the trading patterns, pivot and trends for the day
July 10, 2014 at 10:59 AM
South Africa's new visa laws scare Zimbabwean migrants
July 10, 2014 at 10:47 AM
Congress says complaint against Sonia Gandhi politically motivated
July 10, 2014 at 10:34 AM
Police arrest three Maoists in Jharkhand
July 10, 2014 at 10:28 AM
Holy month of Ramadan spurs rush to buy dates in Kashmir
July 10, 2014 at 8:51 AM