New hope for Liver Cancer patients

New Delhi, Wed, 06 Jun 2007 NI Wire

Sorafenib, an oral pill will protract the survival of the liver cancer patients who have no option except extremely expensive way of liver transplantation. This was claimed by the American scientists who have successfully discovered a new drug that extends the life of the cancer patient from the very advance stage.


American scientists have claimed that Nexavar, the brand name of the Sorafenib drug is the first systemic drug that blocks the formation of blood vessels feeding tumors and also averts the cancerous growth involving rapid cellular and tissue growth. This enhances the chances of survival of the cancer patients up to 44 per cent or about three months. Though a proper drug is yet to be discovered that will completely eradicate the cancer, but this is the first successful step and a major progress in this field.

Liver cancer, the third deadly disease in the world is now curable; according to researchers from the Mount Sinai School of Medicine in New York and Hospital Clinic of Barcelona, Spain. The researchers presented their research report at American Society of Clinical Oncology's annual meeting in Chicago on Monday, June 04. The research report was based on the study of 602 patients suffering from hepatocellular carcinoma, the most common form of liver cancer. The patients were divided into two groups; One group was treated with 400 mgs of single Nexavar (Sorafenib) tablet, given twice a day, while the other group was treated in the same pattern by a dummy for two years, from March 2005 to February 2007. “All patients had no more than six months life before the experiment began,” said a researcher. “The result was amazing. On an average, the patient who received treatment with Sorafenib survived till 10.7 months while the other group of patient could live up to 08 months only. This experiment has opened new avenues regarding the treatment of liver cancer.”

According to World Health Organization WHO, more than 6,22,000 people across the world die because of this fatal disease. The disease is very much related to Hepatitis B and C virus. The exposure of these viruses is the primary reason of this fatal disease, but smoking and liquor is also among the main reason of lever cancer. It is very difficult to diagnose this disease at the early stage, that’s why most of the patients are detected with chronic cancer at the advance stage. It is often too late for a proper cure. If it is detected in the early or second stage, then lever transplantation is the only way to save the life of the patient. But this process is extremely expensive. The surgical procedure costs about 15 lacs (in Indian currency). After that the patient has to go for oral treatment to prevent the rejection of the transplanted organ.

Sorafenib is the only way of curing the patient at the advanced stage, when surgery and radio therapy does not work, claims Emeryville Biotechnology Company, the developer of Sorafenib. Nexavar has already been approved for treating kidney cancer and experiments are being conducted for other cancer types, including melanoma, lung cancer and breast cancer. Onyx, a US pharmaceuticals company with its German partner, Bayer Pharmaceuticals Corp, have planned to ask the Food and Drug Administration of USA for getting approval of Nexavar in treating the liver cancer. These pharmaceutical companies have developed Nexavar as a joint project. The decision may come by early 2008, Onyx chief executive Hollings Renton said. “The estimated cost of this treatment would be approximately $4500 per month,” added the CEO.

A market expert has analyzed that the estimate sale of Nexavar could reach over $1 billion by 2011, with $745 million in treatments for liver cancer, while Onyx's shares had gained $2.64 to close at $33.52 on Monday, June 04.



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Comments:

zeeshan shafique

September 25, 2010 at 12:00 AM

my mother has cirrhosis of the liver and my doctor told me make a ct scan 2day i m v v upset she is not feeling well most of the time she feel fever plz tell me any medicine to beat this . and also tell me where i can buy the medicine in pakistan plz tell me i m cryng when i m writing thes words zeeshan from islamabad 24/09/2010

chiranjib

August 18, 2010 at 12:00 AM

my uncle has got liver cancer. he is in last stage. is there any scope of cure-ness. he has been also attacked by jondis. plz let me know the your comment

.Amey Rathi

July 11, 2010 at 12:00 AM

sir,my grand father suffer liver carcinoma.due to some traum,there is injuri to leg.he taking sorafenib as oral chemotherpy for carcinoma.but ulcer does not heal on leg.his health is good.hb-14 wbc count 11000.give me some advice to treat ulcer.for this ulcer ,he taking various antibiotics.so kindly advice me about ulcer tret in him with chemo

Tushar Parekh

June 29, 2010 at 12:00 AM

My mother aged 70Y detected liver cancer. What is suitable treatement out of chemoembolization & surgery. At present symptoms are like loss of appetite, nausea, weakness, abdomenal pain but no vomiting. We have done Sonography & CT scan. AFP is normal. Suspection of primary metastacis in liver is mentioned in the CT report. Biopsy is not done. Minimum ascitis all other blood reports are normal. Also pls let us know what are the side effects of chemoembolization.

arti

May 15, 2010 at 12:00 AM

my father in advance stage of liver cancer i want to save his life at any cost so i want to know about it plz tel me

C N Mukherjee

May 30, 2009 at 12:00 AM

My father has been diagnosed with obstructive jaundice with large hepatic hetrogeneously enhancing mass segment 5/6,4 and caudate lobe with multiple metastasis with dilated IHBR s/o Malignancy, CA, GB with Contagious spread thickened Caecum and Prox ascending colon inflamatory B/L Renal Cortical cyst. Kindly suggest treatment for my father so that he may live.

rakesh

May 15, 2009 at 12:00 AM

im fell very g8 about ur helping the people.but i want spme help fr ur side.my dad is suffering from lever cancer,i think the cancer is in primary stage.im conform when im saw ur website.now my father suffering jandis.plz help me,wt precautions i want to take..plzzzz

sps sawhney

May 1, 2009 at 12:00 AM

my father in law is suffering from liver cancer he is non drnker kindly advise

sps sawhney

May 1, 2009 at 12:00 AM

may i know how to cure patient with lever cancer at advance stage he is non drinker

Pradeep

December 21, 2008 at 12:00 AM

Docters suspect my father is suffering from a liver cancer,he going through the diagnosis process,please be kind enough to give us some information about new liver cancer drug"NEXAVER"and is it available for treatments now, is it available in sri lanka. also please give us your opinion on this situation.

dharmendra chauhan

September 26, 2008 at 12:00 AM

my uncle is suffering from liver cancer,it has been detected recently.Doctor( SGPGI LUCKNOW ) has said that this is the last stage & patient`s life is one month. please suggest me immedietly. also give me some information about liver cancer.

Himanshu Sharma

September 21, 2008 at 12:00 AM

My mother was operated for colon cancer in january 2008 and in April 2008 on performing the ultrasound test, it showed that she is suffereing from METASTATIC COLON CANCER TO THE LIVER. after 8 sessions of chemotheraphy the liver cancer cells are dead but now after a detailed CT-scan in sep 2008 , metastatic were found at colon and in 2 other body parts,
kindly suggest something for better treatment and for increasing her life expectency ,
Any help would be higly Appreciated.

Faria zarrin

September 19, 2008 at 12:00 AM

My aunty is suffering from liver cancer,it has been detected recently,she was initially suffering from breast cancer which was treated,but now the cancer has spread to the liver. Can you please suggest me the best place to get treated in india as well as abroad.Please reply.

vijai

September 18, 2008 at 12:00 AM

sir accually my friend has a lung cancer he is under treatment in appolo banglore now the recent scan shows that it has been spread in liver too. please suggest me immedietly.

sunny anand

September 15, 2008 at 12:00 AM

may i know that is there a cure of liver cancer?
which is the best liver cancer hospital in india?
is university of alabama at birmingham better place to show?also give me some information about liver cancer?

GA SWAMY

September 13, 2008 at 12:00 AM

Sir, my father has suffering from liver cancer 4th stage, vat can i do

feroz

September 4, 2008 at 12:00 AM

my mother was operated for colon cancer in january 2008 and these month on performing the ultrasound test, it showed that she is suffereing from METASTATIC COLON CANCER TO THE LIVER.
please suggest something and would chenmotheraphy will help in reducing the growth of cancereous cells and extend the life period.
plz inform

Gufran Ajmal

August 30, 2008 at 12:00 AM

I want to know about more of lever cancer. my uncle is suffering from this disease since last six month and doctor(of tata hospital, mumbai, India{Dr. Menon}) has already said that this is the last stage and no option left even lever transplant. So plz do something Plz PLz. My uncle is a Indian Railway employee and no matter of medicine in India and Abroad also.

kandasamy Damodaran

July 31, 2008 at 12:00 AM

my Fater has been diagonised with lever cancer anmd doctor told us that there is large 137*123*99 heterogenous mass involving segement 4.5 and 8 of liver.They told us that it is in advanced stage and there is no treatemnt.
I would like to know that is there is any treatment avaiable in India and I read this article any idea about where can we get th medicine. We are from southern part of India,Coimbatore, Tamil.
Please help me.

Arif Mahmud

July 21, 2008 at 12:00 AM

Patient is my aunt which Tumer cancer in stomack(different sizes)which spread in full stomack and also affected lever.Age is 32.from bangladesh.pls advise at soonest.thanking you.
Could you pls advise is this possible tratment in India ?

Shanoj

July 18, 2008 at 12:00 AM

My uncle is suffering from liver cancer, he is in the last stage. The pain started only a few months back what could be done. Which pain killer is best

gyaendu

May 5, 2008 at 12:00 AM

My father is suffering liver cancer,rite now he is faacing pain in leaver as well as some part of body portion.He cant move any where so we are unable to take him to hospital also.What we will do to relief from pain and for further treatment.
plz>>>plz....suggest me.

nidihi

May 2, 2008 at 12:00 AM

Hi my self nidhi iam safring of lever cancer but i made opration it was sucufull.everything was going well but sudenly i got the news from doctor that you again got same disecess so please let me know the right way that what do i do

Sikandar

April 17, 2008 at 12:00 AM

My uncle is heart patient from 1990 as shown by angeography. He is diabetic for one year. his blood pressuer is almost 170/110. Now he suffer leveroasis. He wants lever transplantation from India. please suggest me how and where. My uncle lives in Pakistan.

venu kumar

April 4, 2008 at 12:00 AM

my grandmother is suffering liver cancer treatment is going on in asian instuite of madicals in hydrabad.so pls saguest for batter treatment.

FATEMA RUNA

March 30, 2008 at 12:00 AM

MY FATHER IS SUFFERING FROM LEVER CANCER.PLZ ADVISE ME WHERE WE FIND BETTER TREATMENT FOR THIS DISEASES?

ashish baviskar

March 19, 2008 at 12:00 AM

My father is suffering from lever cancer, treatement is going on in TATA memorial hospital Mumbai Suggest me is it curable?

kishore kumar

March 1, 2008 at 12:00 AM

My father is suffering from lever cancer please advise some useful tips

Moon

February 23, 2008 at 12:00 AM

My father is suffering liver cancer,can we buy in Indonesian,we're from Indonesian,how much? I want to know detail of this medicine are the medicine has effect to patient,please reply thx

Pradipta

February 3, 2008 at 12:00 AM

My Brother in law is suffering metastatic liver cancer with primay source from lung. while the tumor in the lung is controlled the cancer is spreading in the liver. Is there any way sorafenib can help

Dharam Pal Angra

October 31, 2007 at 12:00 AM

My wife has been diagonised with lever lessions in one of the lobes of size 1.6cmsX2.8 cms. Can this medicine help her to cure. Where can I buy this medicine? How much is cost?

Narendra Keshavji

October 30, 2007 at 12:00 AM

My uncle is suffering from lever cancer and has HIB virus and may be Hepatocellular carcinoma caused by cirrhosis of lever. Please let me know if this drug can help and to what extent it can help. Please let me know where it can be available and if insurers like Norvich Union can provide it. Thanks. Please reply soon.

manisha.p.s

July 30, 2007 at 12:00 AM

Require more details about the medicine

Lala

July 29, 2007 at 12:00 AM

my father has cirrhosis of the liver and we almost lost him 2 months ago. And I think that his not feeling well this past few weeks, can this medicine help my father? We're from the Philippines, where can I buy this medicine. PLs help...