Search: Look for:   Last 1 Month   Last 6 Months   All time
Home :: World

New insights into fatty liver disease

United States,Health/Medicine, Tue, 11 Feb 2014 IANS

New York, Feb 11 (IANS) In major find, scientists have discovered a biological switch that regulates a protein that causes fatty liver disease.

"We have learned how the body finely tunes levels of a protein called SCAP that is required to turn on fat production in cells," said Peter Espenshade, professor of cell biology at Johns Hopkins University School of Medicine.

"We hope this new information would eventually lead to interventions that could help people suffering from obesity-induced fatty liver disease and diabetes," he added.

Fats, which include cholesterol, are essential to the life of organisms but too much can sabotage systems that rid the body of toxins and regulate hormones, among other functions.

Crucial to the right balance of fats is a family of proteins called sterol regulatory element-binding proteins (SREBPs), which turn on fat-making genes when fat levels in cells are low.

The protein SCAP binds to SREBP before they both make their way to the cellular compartment known as the Golgi.

"We knew lots about this first part of the cycle, but we didn't know what happened to SCAP after it 'dropped off' the SREBP," said Espenshade.

"We don't know what is responsible for freeing SCAP from SREBP but we now understand that SCAP keeps the cycle going," added Espenshade.

"Since SCAP is so central to fat production, we hope this improved understanding of its activity would help develop drugs to better regulate the process, he hoped.


LATEST IMAGES
PM Modi releasing the digital version of Ramcharitmanas
Chief Minister of Punjab calling on the PM Modi
A group of girl students from the Vatsalya Gram Vrindavan tied Rakhi on PM Modi
President of India with the artists after witnessing a performance
President with the Children, on the occasion of 'Raksha Bandhan'

We Are Your Friends Flops at Box Office
September 1, 2015 at 12:26 AM

Yachts set off on round-the-world race
September 1, 2015 at 12:24 AM

Tom Brady's Sketch Artist Fails Again!
September 1, 2015 at 12:19 AM

Migrant crisis forces EU to seek answers
September 1, 2015 at 12:02 AM

Justin Timberlake Reacts to Kanye's Jab
August 31, 2015 at 11:56 PM

Iraq retakes territory from Islamic State: army
August 31, 2015 at 11:29 PM

View More Videos
Post comments:
Your Name (*) :
Your Email :
Your Phone :
Your Comment (*):
  Reload Image
 
 

Comments:


 

OTHER TOP STORIES


Excellent Hair Fall Treatment
Careers | Privacy Policy | Feedback | About Us | Contact Us | | Latest News
Copyright © 2015 NEWS TRACK India All rights reserved.