Search: Look for:   Last 1 Month   Last 6 Months   All time

New therapeutic target for Alzheimer's disease identified

Washington, Fri, 02 Nov 2012 ANI

Washington, November 2 (ANI): A new study has identified an enzyme called Monoacylglycerol lipase (MAGL) as a potential therapeutic target to treat or prevent Alzheimer's disease.

The research team found that inactivation of MAGL, best known for its role in degrading a cannabinoid produced in the brain, reduced the production and accumulation of beta amyloid plaques, a pathological hallmark of Alzheimer's disease.

Inhibition of this enzyme also decreased neuroinflammation and neurodegeneration, and improved plasticity of the brain, learning and memory.

"Our results suggest that MAGL contributes to the cause and development of Alzheimer's disease and that blocking MAGL represents a promising therapeutic target," said lead researcher Dr. Chu Chen, PhD, Associate Professor of Neuroscience at LSU Health Sciences Center New Orleans.

"There is a great public health need to discover new therapies to prevent and treat this devastating disorder," Dr. Chen concludes. The research was supported by grants from the National Institutes of Health.

The study was recently published in the Online Now section of the journal Cell Reports. (ANI)


PM Modi being received by the President of France
PM Modi being received on his arrival at Paris to attend COP21 Summit
PM Modi arrives at Paris to attend COP21 Summit
Pranab Mukherjee presenting the Standard to the 18 Squadron of Indian Air Force
PM Modi speaking in the Lok Sabha
Post comments:
Your Name (*) :
Your Email :
Your Phone :
Your Comment (*):
  Reload Image




Excellent Hair Fall Treatment
Careers | Privacy Policy | Feedback | About Us | Contact Us | | Latest News
Copyright © 2015 NEWS TRACK India All rights reserved.