'One-size-fits-all' approach may not always work when treating BP in diabetics

Washington, May 29 (ANI): Aggressive efforts to lower blood pressure in people suffering from diabetes are paying off and possibly too well, say researchers.

The research shows that there have been dramatic improvements in blood pressure control among patients with diabetes in the U.S. Department of Veterans Affairs, with as many as 82 percent of patients having blood pressure controlled and 94 percent getting appropriate BP treatment.

However, given the dramatic rise in control, many people now may be getting over-treated with blood pressure medications rather than being under-treated.

A team of researchers from the VA Ann Arbor Healthcare System and the University of Michigan Health System suggest that it might be time to reconsider the current 'one-size-fits-all' approach to blood pressure control, and turn to a new model that adjusts the blood pressure goal according to the individual.

According to them a modern healthcare electronic record systems should help make this possible because blood pressure, prescription and other health data on individual risks such as heart disease or balance problems can all be combined.

In the research, the team found that, over 8 percent of the 977,000 VA patients nationwide, who were afflicted with diabetes are possibly being over-treated.

Moreover, 6 percent were not being treated as aggressively as they could be.

"Appropriately treating blood pressure in people with diabetes is extremely important, and good blood pressure control should still be the goal to reduce risk of heart attack, stroke and other conditions," said first author Eve Kerr, M.D., director of the Center for Clinical Management Research at the VAAAHS and professor of internal medicine at the U-M Medical School.

"But just treating to a BP target in all patients may result in over-treating and harming some patients because their blood pressures actually fall too low," she said.

"We need to find better ways to measure and incentivize appropriate BP management to make sure that patients who need aggressive treatment are getting it, and to decrease the rate of inappropriate over treatment," said Kerr.

The team analyzed electronic records from people with diabetes and high blood pressure who were treated at any of 879 VA hospitals and clinics in 2009 and 2010.

Approximately, 714,000 of them were between the ages of 18 and 75.

Concluding from the expertise of dozens of VA clinical and measurement experts, they developed a "clinical action measure", or way of assessing the appropriateness of a patient's care by looking at treatment factors and contraindications, not just the target blood pressure.

They also defined a monitor of potential over treatment, to indicated that some patients could be receiving overly aggressive treatment.

A suitable BP management was defined by the clinical action measure having a BP either less than 140/90 or less than 150/65; or having appropriate management of elevated blood pressure (medication intensification or being on 3 or more BP medications).

Meanwhile, potential over treatment was defined as having blood pressure that was less than 130/65 while also receiving three or more BP medicines or having recent medication increases.

They focused on the patients under the age of 75 while assessing under-treatment, and all patients when looking for over treatment.

Recent research has discovered that patients with diabetes don't have better cardiovascular outcomes, but experience more side effects, if they get aggressive treatment to lower their blood pressure under 130/80.

Meanwhile, some people experience side effects caused by 'Polypharmacy', or the impact of taking multiple drugs at the same time for the same condition.

In addition to it, diastolic blood pressure under 65 is linked with worse cardiovascular health, and low blood pressure could also cause dizziness that can lead to dangerous falls.

Interestingly, the rate of over treatment varied considerably between VA facilities - some ranged as high as 20 percent while some went as low as 3 percent.

They found that the hospitals and clinics with the highest overall rates of diabetes patients with blood pressure at or below the target of 140/90 also had the highest rates of over treatment.

According to Kerr, a member of the U-M Institute for Healthcare Policy and Innovation and the Michigan Diabetes Research and Training Center, such a result is expected when focus was on a target than on an individualized approach - a phenomenon that might be tied to performance incentives and public reporting practices currently in place.

Such one-goal-for-all benchmarks were set years ago when blood pressure control for people with diabetes was poor in a general sense.

Kerr insists that now, when 82 percent of VA patients with diabetes have their blood pressure under 140/90, a more sophisticated approach is likely needed.

"We need to have performance measures that focus on appropriate treatment, and if patients are being treated aggressively but still don't quite get to a target control value we need to allow that to count as appropriate care," she said.

As a first step, the VA system will adopt the BP clinical action measure to encourage appropriate BP management for patients based on their risks and treatment characteristics.

However, the same could be done in non-VA settings, especially those that have reached as high levels of BP control as has the VA healthcare system.

According to Kerr, people who have diabetes should talk with their doctors about their blood pressure treatment and the lifestyle steps and medicines they are taking to keep it under control

"It is essential that we continue to monitor and focus on BP control among patients with diabetes, but we also have to realize that when BP starts to dip too low, it may be time to decrease treatment," she added.

The study has been published in the Archives of Internal Medicine. (ANI)