World's 1st bedside gene test gets green light by leading medical journal

Washington , Fri, 30 Mar 2012 ANI

Washington, Mar 30 (ANI): The world's first bedside genetic test, which was developed in Canada and conducted by researchers from the University of Ottawa Heart Institute in partnership with Spartan Bioscience, has received acknowledgment by an esteemed medical publication The Lancet.

The article Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial, reports the use of a simple cheek swab test, the Spartan RX CYP2C19, performed by nurses at the patient's bedside.

This revolutionary technology allows doctors to rapidly identify patients with a genetic variant known as CYP2C19*2. Cardiac stent patients with this variant are at risk of reacting poorly to standard anti-platelet therapy with Plavix (clopidogrel).

The study demonstrated that tailored drug treatment therapy made possible by the genetic testing successfully protected all of the patients with the at-risk genetic variant from subsequent adverse events, while 30 per cent of patients treated with standard therapy did not receive adequate protection.

"For the first time in medicine, nurses were able to perform DNA testing at the patient's bedside. This is a significant step towards the vision of personalized medicine," Derek So, principal investigator of the study from the University of Ottawa Heart Institute (UOHI), said. (ANI)



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